Dr. Martey holds a PhD and an MPhil in Pharmacology from University of Otago, New Zealand and Tianjin University of TCM, China and BSc in Biochemistry from the University of Ghana, Legon. He joined the Centre in 2005 as an Assistant Research Officer in the Pharmacology/Toxicology Department and has risen to the position of Research Officer currently.

Research Interests Breast cancer, nanomedicine, drug metabolism and drug-herb interaction (Cyp450 and P-glycoproteins), safety assessment, histopathology, antimalaria, diabetes, hypertension, antidiarrhea

PUBLICATION RECORD

Orleans NK Martey, Khaled Greish, Paul F Smith, Rhonda J. Rosengren, (2019). A Multivariate Statistical Analysis of styrene maleic acid encapsulated RL71 in a xenograft model of triple negative breast cancer. J. Biol. Methods 6 (4):e121 DOI10.144440/jbm.2019.306.

Shrestha N, Lateef Z, Martey O et al. (2019). Does the mouse tail vein injection method provide a good model of lung cancer? [version 1; referees: awaiting peer review] F1000Research, 8:190 (https://doi.org/10.12688/f1000research.17964.1)

Antwi S., Asiedu-Larbi J., Martey ONK., Quasie O., Boakye-Yiadom M., Ayertey F., Yeboah R., Sapaty CA., Kumatia EK., Ocloo A., (2019). Safety and Effectiveness of Mist Antiaris, a Herbal Preparation for Treatment of Peripheral Neuropathy. BioMed Resh Inter., ID 2607872. (https://doi.org/10.1155/2019/2607872).

 

Saka P., Osafo KE., Antwi S., Martey ONK., Quasie O., Antwi-Adjei M., Asiedu-Larbi J., Takyi NK., Donkor KN., Okine LKN., (2018). The Anti-dyslipidemic Effects of Milled Root Bark Ethanolic Extract of Capparis erythrocarpus in Sprague-Dawley Rats: Implications for Obesity and Cardiovascular Diseases. J. Applied Pharmaceu. Sci., 8 (01), 1-8.  DOI: 10.7324/JAPS.2018.8101 (http://www.japsonline.com).

 

Martey, O, Ninick, M., Taurin, S., Sundararajan, V., Greish, K. and Rosengren R.J., (2017). Styrene maleic acid-encapsulated RL71 micelles suppress tumor growth in a murine xenograft model of triple negative breast cancer, Int. J.  Nanomedicine 12:7225-7237. 

Liang, S. Deng F.C., Xing H., Wen H., Shi, X., Martey, O. N. Emmanuel, K., He. X. (2014). P-glycoprotein and Organic anionic-transporting polpypeptide-mediated transport of periplocin may lead to drug-herb/drug-drug interactions. Drug Des, Devel. Ther. 8:475-489.

Martey, O.N.K., He, X., Xing, H., Chuang, D., Sheng, F., Li, C., Shi, X., (2014). Periplocymarin is a potential natural compound for drug development: Highly permeable with absence of P-glycoprotein efflux and cytochrome P450 inhibitions. Biopharm. Drug Dispos 35 (4): 195-206, DOI: 10.1002/bdd.1884.

Martey. O.N.K., Shi, X., He, X., (2013). Advance in Pre-Clinical Pharmacokinetic of Paeoniflorin, a major monoterpene glucoside from the root of Paeonia lactiflora. Pharmacol and Pharm. 4: 4-14.

Donkor, K., Antwi, S., Asiedu-Larbi, J., Takyi, N., Martey, O.N., (2013). Analgesic and anti-inflamatory activities of Asena, a herbal preparation for treatment of arthritis, using rodent model. Medicinal and aromatic plant research journal, 1 (2): 20-29.

Martey, O.N.K., Shittah-Bay, O., Owusu, J., Okine, L.K.N., (2013). The Antiplasmoodial activity of herbal Antimalaria, AM 207 in plasmodium berghei-infected Balb/c Mice: Absence of Organ Specific Toxicity. J. Med. Sci., 13 (7): 537-545.

Martey, O.N.K., Armah, G.E., Sittie, A.A., Okine, L.K.N., (2013). A Chronic Toxicity Study of the Ground Root Back of Capparis erythrocarpus (Cappareceae) in male Sprague-dawley rats. Pak. J. Biol., Sci., 16 (23): 1706-1713.

Xin He, Shan Feng, Yuefei Wang, Chao Li, Jipeng Hou, O. N. K. Martey and Changxiao Liu (2010). Herb-Drug interaction: effect of isopeulustrin on the metabolism and pharmacokinetics of tetramethylpyrazine by in vivo and in vitro methods. 18th International Society for the Study of Xenobiotics vol. 42, No. S1, PP i-I (doi: 10.3109/03602532.2010.506065).

Martey, O.N.K and He X., 2010. Possible Mode of Action of Mondia whitei: An Aphrodisiac Used in the Management of Erectile Dysfunction J. Pharmacol. Toxicol 5 (8): 460-468.

Martey, O.N.K., Armah, G.E. and Okine, L.K.N. (2010). Absence of organ specific toxicity in rats treated with Tonica, an aqueous herbal haematinic. J. Trad. CAM, 7(3): 231-240.

Quasie, O., Martey, O.N.K., Nyarko, A.K., Gbewenoyo, W.S.K. and Okine, L.K.N. (2010). Modulation of penile erection in rabbits by Mondia whitei: Possible mechanism of action. J. Trad. CAM, 7(3).241-252.

Martey, O.N.K., Ocloo, A., Koomson, E. and Okine, L.K.N. (2009). Assessment of Tonica, an aqueous herbal haematinic, in the modulation of rat hepatic microsomal CYP-mediated drug metabolizing enzymes: Implications for drug interactions. J. Pharmacol. Toxicol 4 (2): 70-78.

Antwi, S., Martey, O.N.K., Donkor, K.N. and Okine, L.K.N. (2009). Antidiarrhoeal activity of Blighia sapida (Sapindaceae) in rats and mice. J. Pharmacol. Toxicol 4 (3): 117-125.

Okine, L.K.N., Armah, G.E., Awumbila, B., Martey, O.N.K. and Ofosuhene, M. (2004). Acute and sub-chronic toxicity studies of Add-203, a fermented ground seed extract of Cassia occidentalis, in male Spraque-dawley rats. J. Ghana Sci. Assoc. 6:30-38.